Prostate
PSA blood test
A PSA blood test measures prostate-specific antigen, a protein made by the prostate gland, and it is used to help assess prostate health in men. On its own it cannot diagnose or rule out prostate cancer: PSA rises with age and with several harmless conditions, so a result is always interpreted with your age, symptoms and an examination.
- What it measures
- Prostate-specific antigen (a prostate protein)
- Sample
- Venous blood sample
- Fasting
- Not required
- Also known as
- prostate-specific antigen, prostate profile
- Included in 57 Health tests
- 3 panels, from £140
What does a high PSA level mean?
A raised PSA means more of the protein is reaching your blood, but it does not mean you have cancer. The most common causes are an enlarged prostate (very common with age), a prostate or urine infection, and recent activities that irritate the gland, such as ejaculation, vigorous exercise or cycling, a recent catheter or a rectal examination.
Because of this, a single raised result is usually repeated, often after a few weeks and after avoiding those triggers, and is considered alongside your symptoms and an examination. If concern remains, the next step is a discussion with a doctor about further assessment, which may include an MRI scan, rather than drawing conclusions from the number alone.
What does a low PSA level mean?
A low PSA is generally reassuring, and it is what most men without a prostate problem will have. There is no lower limit to worry about.
It is worth knowing that some medicines for an enlarged prostate or hair loss (finasteride and dutasteride) roughly halve PSA, so a result can look reassuringly low while you take them. Tell whoever interprets your test if you take one of these, so the figure can be read correctly.
When to consider a PSA test
- Urinary symptoms: a weak flow, going more often, or at night
- A family history of prostate cancer
- Being over 50 and wanting an informed baseline
- Black ethnicity, which carries a higher prostate-cancer risk
- Ongoing monitoring agreed with your doctor
Frequently asked questions
This page is general information about a blood marker and is not medical advice or a diagnosis. A PSA test screens and gives context; results are interpreted by a clinician alongside your symptoms, history and other markers. Always follow the guidance on your own report.